Palazzina Grassi

In a 1500s building, this ultrachic luxury hotel by renowned designer Philippe Starck is a 4-minute walk from a vaporetto stop on the Grand Canal. It's 11 minutes on foot from the Peggy Guggenheim Collection modern art museum. Featuring multiple mirrors and contemporary furniture, the striking, fashionable rooms have flat-screens, minibars and Wi-Fi. Upgraded rooms offer balconies and/or coffeemakers. Suites provide sitting areas or separate living rooms; some add canal views and/or sofabeds. There's a stylish fine-dining restaurant with Murano glass chandeliers and a seasonal terrace, plus a plush champagne lounge. Breakfast is available.